Ontonix Publishes Article in Biomedical Journal of Science and Technology

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Como, 5-th May, 2023. Ontonix Publishes Article in Biomedical Journal of Science and Technology on “Protein Folding – Quantification of Protein Complexity, Robustness and Amino Acid Participation”. The QCT (Quantitative Complexity Theory) algorithm has been applied to the analysis of the folding process of a protein composed of 435 atoms, monitoring its complexity at each step thereof. The folding has been simulated using Molecular Dynamics Simulation. The analysis has revealed that, while in the native state, the protein’s configuration minimizes its energy, its complexity reaches a maximum.

The experiment described in the paper illustrates how complexity can be used to measure the robustness of a protein, which may be linked to its longevity, as well as determine teh degree of participation of each amino acid in the protein’s global properties.

Dowload the article.

Biomedical Journal of Scientific & Technical Research (BJSTR - www.biomedres.us) is a multidisciplinary, scholarly Open Access publisher focused on Genetic, Biomedical and Remedial missions in relation with Technical Knowledge as well.

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Dr. Jacek Marczyk

Visionary, ex rocket scientist, businessman and writer with over 35 years of experience in QUANTITATIVE large-scale Uncertainty and Complexity Management in diverse fields (manufacturing, finance, economics).

Author of ten books on simulation, uncertainty and complexity management, rating.

Developed in mid 90s the theory of eigenvalue orbits, a generalization of the concept of eigenvalue.

In 2000-2005 has developed the first Quantitative Complexity Theory (QCT), including a comprehensive measure of complexity.

Founded Ontonix Complexity Management in 2005 in the USA and launched in 2006 the first commercial system for MEASURING and managing complexity: OntoSpace.

www.ontonix.com

In 2009 developed real-time technology to measure the complexity and stability of patients during operation or permanence in Intensive Care Units.

http://www.ontomed.net

Developed a new theory of risk and rating published in 2009 in a book entitled "A New Theory of Risk and Rating".

Over last decade develops quantitative complexity management (QCM) technology and solutions for applications in economics, finance, Risk Rating and Management as well as in Asset Management and medicine. In the past five years works towards the democratization of ratings.